Reconstitution calculator · Ipamorelin

Ipamorelin reconstitution calculator.

Work out the concentration of a reconstituted Ipamorelin vial. Presets match the 10 mg format we stock, and the reference table below is calculated for those exact vials. Research use only.

Vial size

This tool reports concentration only. It is not dosing guidance, and nothing here is for human use.

Ipamorelin concentration reference table

Every combination of the Ipamorelin vial sizes we stock and the bacteriostatic water volumes people most often add.

VialBAC waterConcentrationPer 100 µL aliquot
10 mg1 ml10 mg/ml1 mg (1,000 mcg)
10 mg2 ml5 mg/ml0.5 mg (500 mcg)
10 mg3 ml3.333 mg/ml0.333 mg (333 mcg)
10 mg5 ml2 mg/ml0.2 mg (200 mcg)

How the calculation works

Concentration is the mass of peptide divided by the volume of solvent. A vial holding 5 mg reconstituted with 2 ml of bacteriostatic water gives 2.5 mg/ml, so a 100 µL aliquot contains 0.25 mg. The powder itself adds no meaningful volume at these masses, which is why the water volume alone sets the concentration.

Handling in the Vietnamese climate

Sealed lyophilized vials are stable at room temperature in transit, which is why the material ships dry rather than cold. Once reconstituted, the solution is kept refrigerated and shielded from light. Bacteriostatic water is the usual solvent because the benzyl alcohol in it lets a vial be entered more than once.

What is Ipamorelin?

A five-amino-acid growth hormone secretagogue, known in the literature as the most selective of its class.

Ipamorelin is a synthetic pentapeptide developed at Novo Nordisk in the 1990s. It binds the ghrelin receptor (GHS-R1a) in the pituitary, which is the same receptor family the older GHRPs act on. But it was specifically engineered to do so cleanly.

That selectivity is the whole point of the molecule. Earlier secretagogues like GHRP-6 and GHRP-2 also push cortisol, prolactin and ACTH; published work on ipamorelin found it raises growth hormone with little measurable effect on those other hormones. Novo Nordisk took it into human trials for post-operative ileus and stopped development after phase 2, so it has never been approved anywhere and remains a research compound.

Research context

Type
Synthetic pentapeptide (5 amino acids)
Target
Ghrelin receptor GHS-R1a in the pituitary
Origin
Novo Nordisk, 1990s; development stopped after phase 2 trials
Distinguishing trait
Most receptor-selective of the growth hormone secretagogues
Format
Lyophilized powder in a sealed vial
Ipamorelin product page

Common questions

What is Ipamorelin?

A synthetic five-amino-acid peptide that acts on the ghrelin receptor to trigger growth hormone release from the pituitary. It was developed by Novo Nordisk, never approved anywhere, and is listed here as a non-clinical research material only.

How is Ipamorelin different from CJC-1295 or Tesamorelin?

Different receptors. CJC-1295 and Tesamorelin are GHRH analogs. They mimic the hypothalamic hormone that tells the pituitary to release GH. Ipamorelin works through the ghrelin receptor instead, which is why the two mechanisms are often studied side by side rather than as substitutes.

How much bacteriostatic water do I add to a Ipamorelin vial?

There is no single correct volume. The water volume sets the concentration: more water gives a weaker solution and a larger aliquot for the same mass. Common choices are 1 to 5 ml. Enter your vial size above to see what each volume produces for 10 mg.

What concentration does a Ipamorelin vial give?

It depends entirely on the solvent volume. The reference table above lists every combination of the 10 mg vial format and 1, 2, 3 and 5 ml of bacteriostatic water.

Does the powder change the final volume?

Not measurably at these masses. A few milligrams of lyophilized peptide occupies a negligible volume, so the bacteriostatic water you add is effectively the final volume.

Can I use normal water or saline instead?

Bacteriostatic water is the standard solvent for multi-entry vials because it contains a preservative. Sterile water and saline have no preservative, so they are single-entry solvents.

Check Ipamorelin availability

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