Cellular research
Ipamorelin
Selective GH secretagogue, pentapeptide
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Research use only
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What is Ipamorelin?
A five-amino-acid growth hormone secretagogue, known in the literature as the most selective of its class.
Ipamorelin is a synthetic pentapeptide developed at Novo Nordisk in the 1990s. It binds the ghrelin receptor (GHS-R1a) in the pituitary, which is the same receptor family the older GHRPs act on. But it was specifically engineered to do so cleanly.
That selectivity is the whole point of the molecule. Earlier secretagogues like GHRP-6 and GHRP-2 also push cortisol, prolactin and ACTH; published work on ipamorelin found it raises growth hormone with little measurable effect on those other hormones. Novo Nordisk took it into human trials for post-operative ileus and stopped development after phase 2, so it has never been approved anywhere and remains a research compound.
Selective GHS-R1a (ghrelin receptor) agonism
Growth hormone pulse patterns without cortisol or prolactin shift
Comparative research against GHRP-2, GHRP-6 and GHRH analogs
Listed for non-clinical research only. Not for human use.
Available options.
Ipamorelin
What is Ipamorelin?
A synthetic five-amino-acid peptide that acts on the ghrelin receptor to trigger growth hormone release from the pituitary. It was developed by Novo Nordisk, never approved anywhere, and is listed here as a non-clinical research material only.
How is Ipamorelin different from CJC-1295 or Tesamorelin?
Different receptors. CJC-1295 and Tesamorelin are GHRH analogs. They mimic the hypothalamic hormone that tells the pituitary to release GH. Ipamorelin works through the ghrelin receptor instead, which is why the two mechanisms are often studied side by side rather than as substitutes.
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