Reconstitution calculator · PT-141
PT-141 reconstitution calculator.
Work out the concentration of a reconstituted PT-141 vial. Presets match the 10 mg format we stock, and the reference table below is calculated for those exact vials. Research use only.
This tool reports concentration only. It is not dosing guidance, and nothing here is for human use.
PT-141 concentration reference table
Every combination of the PT-141 vial sizes we stock and the bacteriostatic water volumes people most often add.
| Vial | BAC water | Concentration | Per 100 µL aliquot |
|---|---|---|---|
| 10 mg | 1 ml | 10 mg/ml | 1 mg (1,000 mcg) |
| 10 mg | 2 ml | 5 mg/ml | 0.5 mg (500 mcg) |
| 10 mg | 3 ml | 3.333 mg/ml | 0.333 mg (333 mcg) |
| 10 mg | 5 ml | 2 mg/ml | 0.2 mg (200 mcg) |
How the calculation works
Concentration is the mass of peptide divided by the volume of solvent. A vial holding 5 mg reconstituted with 2 ml of bacteriostatic water gives 2.5 mg/ml, so a 100 µL aliquot contains 0.25 mg. The powder itself adds no meaningful volume at these masses, which is why the water volume alone sets the concentration.
Handling in the Vietnamese climate
Sealed lyophilized vials are stable at room temperature in transit, which is why the material ships dry rather than cold. Once reconstituted, the solution is kept refrigerated and shielded from light. Bacteriostatic water is the usual solvent because the benzyl alcohol in it lets a vial be entered more than once.
What is PT-141?
Also called bremelanotide. A melanocortin receptor agonist that acts in the brain.
PT-141, or bremelanotide, is a cyclic seven-amino-acid peptide with an unusual history: it is a metabolite of Melanotan II. Researchers noticed that when Melanotan II broke down, one of its by-products acted on the nervous system rather than on pigment cells. That by-product was developed separately into PT-141.
It targets melanocortin receptors, mainly MC4R, and acts centrally in the brain rather than on the vascular system. It is an approved medicine in the United States under the name Vyleesi.
Research context
- Melanocortin receptor agonism (mainly MC4R)
- Central nervous system signalling
- Distinction from vascular-acting compounds
- Type
- Cyclic peptide, 7 amino acids
- Also known as
- Bremelanotide
- Origin
- Developed from a Melanotan II metabolite; approved in the US as Vyleesi
- Format
- Lyophilized powder in a sealed vial
- Handling
- Sealed vials are kept cold and out of direct light. Relevant in the Vietnamese climate
Common questions
What is PT-141?
A cyclic seven-amino-acid peptide, also known as bremelanotide, that acts on melanocortin receptors. Mainly MC4R, in the central nervous system. It is approved in the US under the name Vyleesi. Listed here as a non-clinical research material.
How is PT-141 related to Melanotan II?
PT-141 is a metabolite of Melanotan II. Researchers noticed the breakdown product acted on the nervous system rather than pigment cells, and developed it as a separate compound.
How much bacteriostatic water do I add to a PT-141 vial?
There is no single correct volume. The water volume sets the concentration: more water gives a weaker solution and a larger aliquot for the same mass. Common choices are 1 to 5 ml. Enter your vial size above to see what each volume produces for 10 mg.
What concentration does a PT-141 vial give?
It depends entirely on the solvent volume. The reference table above lists every combination of the 10 mg vial format and 1, 2, 3 and 5 ml of bacteriostatic water.
Does the powder change the final volume?
Not measurably at these masses. A few milligrams of lyophilized peptide occupies a negligible volume, so the bacteriostatic water you add is effectively the final volume.
Can I use normal water or saline instead?
Bacteriostatic water is the standard solvent for multi-entry vials because it contains a preservative. Sterile water and saline have no preservative, so they are single-entry solvents.
Check PT-141 availability
Send the product and format in Telegram. Availability and the total are confirmed in writing before payment.