Specialty-format research
Melanotan II
α-MSH analog, pigment pathway
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Melanotan II reconstitution calculator
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Research use only
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What is Melanotan II?
A synthetic analog of the natural pigment hormone α-MSH.
Melanotan II is a cyclic synthetic analog of α-melanocyte-stimulating hormone (α-MSH), the natural signal that tells pigment cells to produce melanin. The natural hormone breaks down in minutes; closing the molecule into a ring made it stable enough to study.
Melanocortin receptor agonism (non-selective)
Melanin and pigmentation pathways
Precursor research leading to PT-141
A vial format is not a use regimen. Clinical and preclinical evidence answer different questions: use the source record above to see the context.
Listed for non-clinical research only. Not for human use.
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Melanotan II
What is Melanotan II?
A cyclic synthetic analog of α-melanocyte-stimulating hormone, the natural signal for melanin production. The ring structure makes it stable where the natural hormone breaks down in minutes. It is not approved in any country and is listed here as a non-clinical research material.
How is Melanotan II different from PT-141?
Melanotan II is non-selective. It activates several melanocortin receptors. PT-141 was developed from one of its metabolites and targets mainly MC4R in the central nervous system.
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